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syndrome blood dermatology differential product rheumatology transfusion activation anemia arteritis comparison dress dsm5 extravascular gca giantcell hemolysis hemolytic immune inflammatory
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... microangiopathy: Thrombotic thrombocytopenic ... Extravascular #Causes ... #hematology #anemia
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
- Transfusion Reactions ... without other cause ... #Transfusion #Reactions ... #hematology #diagnosis ... #comparison #table
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Edema in 70% of cases ... Criteria for Diagnosis ... Exanthematous Pustulosis Management ... DRESS #Syndrome #dermatology ... #diagnosis #management
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
haptoglobin, ↑LDH, etc ... Causes purpura & ... severe thrombocytopenia ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... haptoglobin, ↑LDH, etc ... severe thrombocytopenia ... #Transfusions #diagnosis ... #management #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... antiinflammatory properties e.g ... Tetracyclines etc ... #diagnosis #management ... #Dermatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
leukopenia, anemia, and thrombocytopenia ... Histopathologic criteria ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
not be subtle e.g ... vision changes, etc ... identifies 85 to 95% of cases ... them, but urgent rheumatology ... #Management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
criteria, but the ... superinfection, drug reactions ... Calmette-Guérin (BCG ... : • Drug reaction ... #Management
DSM-5 Criteria for Post Traumatic Stress Disorder (PTSD) Exposure to actual or threatened death, serious injury, or
DSM-5 Criteria for ... and dissociative reactions ... detachment from others etc ... response - #Diagnosis ... Psychiatry #PTSD #Criteria
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