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management blood product activation anemia causes comparison differential extravascular hemolysis hemolytic intravascular macrophage mas rheumatology taco trali transfusions
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... ) - HELLP syndrome ... microangiopathy: Thrombotic thrombocytopenic ... reaction, Paroxysmal ... #hematology #anemia
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Reactions TRALI ... Berlin Criteria ... #Reactions #hematology ... #diagnosis #comparison ... #table
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... haptoglobin, ↑LDH, etc ... purpura & severe thrombocytopenia ... #diagnosis #management ... #hematology #reactions
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Reactions Immune ... haptoglobin, ↑LDH, etc ... purpura & severe thrombocytopenia ... #diagnosis #management ... #hematology #reactions
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Infection (eg ... leukopenia, anemia, and thrombocytopenia ... Histopathologic criteria ... #Diagnosis #Management ... #Hematology #Rheumatology
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