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Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... than females Guillain-Barre ... bulbar muscles Guillain-Barre ... • Areflexia Guillain-Barre ... #treatment #neurology
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Reflex Testing - Causes ... polyneuropathy (e.g ... Guillain-Barré syndrome ... differential #diagnosis #table ... #neurology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... . during manipulation ... Phaeochromocytoma Neurologic ... Anesthesiology #Anesthesia ... Checklist #Diagnosis #Management
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... and cauda equina TREATMENT ... #diagnosis #management ... #neurology
Cardiac Tamponade - Guidelines for Crises in Anaesthesia
Caused by an accumulation of blood, pus, effusion fluid
, e.g. central line ... thoracotomy is a better treatment ... Plan definitive management ... Anesthesiology #Anesthesia ... Checklist #Diagnosis #Management
Intraoperative  Bradycardia - Guidelines for Crises in Anaesthesia
Bradycardia in theatre should not be treated as
remember to tailor treatment ... Consider known drug causes ... (eg. remifentanil ... , digoxin etc) ... Checklist #Diagnosis #Management
Intraoperative Tachycardia - Guidelines for Crises in Anaesthesia
Tachycardia in theatre is often due to inadequate depth
Guidelines for Crises ... remember to tailor treatment ... obtain 12-lead ECG ... Guidelines for crises ... Checklist #Diagnosis #Management
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
trolley, anaphylaxis treatment ... require prolonged treatment ... alternate vasopressor (e.g ... as patient is stable ... Checklist #Diagnosis #Management
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
with previously stable ... heart failure, neurologic ... Causes: • Vascular ... Neurologic disorders ... dysautonomia, and Guillain-Barre
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
• S - Saddle anesthesia ... - Emergency Causes ... Tethered cord • Guillain-Barre ... axial T1 and T2 Treatment ... #neurology