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diagnosis blood differential product reactions signs symptoms syndrome algorithm causes chronic crisis cryofibrinogenemia dermatology electrophoresis erythematosus fatigue gca giantcell indications
Indications for Serum Protein Electrophoresis (SPEP) • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
chemotherapy, etc ... associated with renal ... suspected • Hypercalcemia ... possible malignancy (e.g ... Electrophoresis #SPEP #Hematology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Metabolic • Renal ... Liver Failure • Hypercalcemia ... Neoplastic / Hematologic ... • Rheumatoid Arthritis ... Chronic Obstructive Pulmonary
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cryoglobulin (CG ... thrombophlebitis, pulmonary ... to medium-sized arteries ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
not be subtle e.g ... E.g. 80 yo ESR cutoff ... vision changes, etc ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... . hematologic) ... pancreatitis, protein-losing ... APLA/LAC: • Renal ... Erythematosus #Diagnosis #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
progressing GN • New pulmonary ... and renal abnormalities ... GCA (Giant Cell Arteritis ... with elevated protein ... Differential #Diagnosis #Rheumatology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... hyperphosphatemia, hypercalcemia ... , and possibly renal ... Pulmonary: dyspnea ... Extrapulmonary: ankle arthritis
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
nonerosive inflammatory arthritis ... antiinflammatory properties e.g ... Tetracyclines etc ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
onion-skinning" of arteries ... Management Pearls ... (short-acting, e.g ... #Crisis #rheumatology ... nephrology #diagnosis #management
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
, DIC, hypoTN, renal ... antibodies against proteins ... Hypocalcemia, Hyperkalemia ... Transfusions #diagnosis #management ... #hematology #reactions
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