18 results
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Malabsorption (e.g ... warfarin, DOACs (e.g ... Autoimmune disorders (e.g ... #comparison #diagnosis ... #hematology #deficiency
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
and Management ... Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... #Management #treatment ... #hematology #differential
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Diagnosis: • ... Electrodiagnostic studies - EMG ... #Syndrome #diagnosis ... #management #treatment ... #neurology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... of information (e.g ... non-essential drug/HDS treatments ... vascular disorder (e.g ... #Algorithm #hepatology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
and Management ... hemophilia type (e.g ... Chronic Management ... #Management #treatment ... #hematology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
inflammation (eg ... been reported (eg ... of Hepatitis (eg ... Histology Findings (eg ... #Management #Hepatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Lumbar Puncture, EEG ... Treatment: ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... #management #treatment
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Electrodiagnostic studies (Ex EMG ... and cauda equina TREATMENT ... GBS #Guillain #Barre ... #management #neurology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
organ damage • Treatment ... Low calcium • Treatment ... unless worrisome EKG ... Syndrome #TLS #diagnosis ... #management #hematology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
unit activity on EMG ... of diazepam • EMG ... EMG Studies: ... #Management #treatment ... #neurology