15 results
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
to HDS, drugs, OTC ... non-essential drug/HDS treatments ... Alcohol-related liver disease ... hepatitis #DILI #DrugInduced ... Diagnosis #Algorithm #hepatology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Symptoms of Joint Disease ... categories of joint disease ... mainly or only during ... Joint #Pain #MSK #rheumatology ... approach #workup #differential
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... , Etc. ... valve induced, Etc ... RBC #Morphology #differential ... #diagnosis #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... thrombocythemia), Autoimmune disease ... Diagnosis #Management #treatment ... #hematology #differential
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
uncovered incidentally during ... glucocorticoid treatment ... signs or symptoms (eg ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
juvenile idiopathic arthritis ... idiopathic arthritis ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Differential Diagnosis ... taking a shower and moving ... Gonococcal/Lyme etc ... Joint #pain #Differential ... Diagnosis #MSK #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... • Malignancy (e.g ... . hematologic) ... pancreatitis, protein-losing ... vein thrombosis Hematologic
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
particularly those coming ... very remarkable w/differential ... vision changes, etc ... of the steroid treatment ... Treatment of GCA
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... Evolution: Chronic disease ... Lupusreference #druginduced ... sle #comparison #table ... #rheumatology #