6 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
: - Neuro: AMS ... hydration - Hyperkalemia ... unless worrisome EKG ... #TLS #diagnosis ... #management #hematology
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... with Ca only if EKG ... Walid Malki, MD, MS ... #TLS #oncology ... #management #UricAcid
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... HIV, Influenza, TSS ... Herpes, Coxsackie, etc ... per day until stable ... Differential #Diagnosis #Management
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Diagnosis and Management ... HIV, Influenza, TSS ... Herpes, Coxsackie etc ... per day until stable ... Dialysis for severe hyperkalemia
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
and Management ... Acidosis, Cell Lysis (TLS ... heparinized tube) • ECG ... Elimination (see Table ... Bicarb<22) - avoid NS
Recurrent Polymorphic VT/Torsades de Pointes - Management Algorithm
Drugs that prolong QT interval:
 • Class 1a (quinidine,
Algorithm Drugs ... Syndrome Electrolyte ... Hypomagnesemia • Hypokalemia ... Hypocalcemia (rarely) Treatment ... #Algorithm