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management syndrome rheumatology algorithm als amyotrophic apml arteritis autoimmune behcet biliary central cholangitis cirrhosis clinical cullen cullensign dermatology differentiation disease
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Pathophysiology ... Signs and Symptoms ... Diagnosis: • ... bile ducts Differential ... #workup #hepatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... priapism • Lab values ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... : >3 symptoms, or ... initiation • Differential ... fluid overload, PCC ... #management #hematology
Maculopapular Rashes - THE ALGORITHMIC APPROACH The term maculopapule is a portmanteau, a combination of macule and
diagnosis; however ... rashes but without signs ... diagnosis, which ... pathognomonic for SJS or EM ... #Diagnosis #Dermatology
Non-Infective Endocarditis (NBTE / Marantic Endocarditis) Non-infective endocarditis is also known as: Non-bacterial thrombotic endocarditis (NBTE), Aseptic
left-sided heart valves ... absent How can we differentiate ... pathognomonic signs ... /symptoms or echo ... #pathophysiology
Cullen's sign. Lipase 1,781. Bruising in the skin around the umbilicus. This sign is named after
Pathophysiology: ... Diagnosis and Context ... is not diagnostic ... onset of other symptoms ... #cullensign #em
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... or sed rate): Value ... very remarkable w/differential ... GCA, but normal values ... #Symptoms #Diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
CNS symptoms (headache ... Behcet disease) Differential ... Diagnosis: • Genital ... #management #signs ... #symptoms #rheumatology
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... of UMN and LMN signs ... fasciculations Common Symptoms ... EMG: LMN Signs in ... conditions listed in differential
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... Aldolase levels • EMG ... papules and Gottron sign ... ) • Shawl sign ... #differential #
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