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diagnosis hepatology rheumatology autoimmune causes cholangitis cirrhosis management aih algorithm antibodies associations autoantibodies biliary chemistry diseases erythematosus hypertension infections infectiousdiseases
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
congenital - Primary ... Nonalcoholic fatty liver ... heart failure (chronic ... #Diagnosis #Differential ... #Hepatology #Cirrhosis
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 Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
SLE, autoimmune hepatitis ... Dermatomyositis Anti-LKM (liver ... , Anti-gp210 - Primary ... biliary cirrhosis (PBC ... Endomyseal antibody (EMA
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... • NASH, Chronic ... injury: > 3 • Chronic ... #differential # ... diagnosis #algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
cholestasis → Cirrhosis/Liver ... or higher • Liver ... bile ducts Differential ... Diagnosis: • Viral hepatitis ... diagnosis #workup #hepatology
The 6 C’s of Primary Sclerosing Cholangitis (PSC) PSC is a chronic, cholestatic, immune-mediated disease characterized by
The 6 C’s of Primary ... ) PSC is a chronic ... remain subject to clinical ... #Primary #Sclerosing ... management #summary #Hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs R-value ... of cholestatic disease ... disease: > 2 ... • NASH, Chronic ... chemistry #diagnosis #differential
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
from subclinical disease ... to acute liver ... - Symptoms of chronic ... hepatocellular pattern of liver ... reported (eg AIH-PBC
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
Hypertension - Differential ... >10 mmHg - clinically ... Cirrhosis/acute hepatitis ... sarcoidosis) • Liver ... pregnancy • Primary
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... the context of primary ... Noninfectious hepatitis ... with Lupus: • Chronic
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
• Primarily occurs ... Hematologic malignancy ... (elevations of liver ... : • Clinical ( ... NTM #Infections #differential
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