8 results
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
HELLP - Grafts, Valves ... Drug-associated, PCH ... Defects, Drugs, Liver ... Defects: Sickle cell anemia ... #Diagnosis #hematology
Vibrio Vulnificus skin infection
Cirrhosis w/recent consumption of raw oysters w/rapidly evolving rash. 
Vibrio vulnificus part of
Hippocrates in 5 BC ... sepsis: chronic liver ... hemochromatosis, hemolytic anemia ... #dermatology #legs ... #clinical #photo
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... • Autoimmune diseases ... appreciate the value ... #differential # ... #CBC #hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... • Symptoms of anemia ... Blood smear - RBC ... younger pts) Differential ... #hematology #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... Malignancy (e.g. hematologic ... lymphopenia, low PLT • Anemia ... titers > 1:80 • CBC
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... www.ncbi.nlm.nih.gov/pmc ... to bolus these values ... presentations and disease ... 30mmHg) - Severe anemia
Melioidosis - Skin Infection
63M h/o diabetes with c/o fever, chest pain, dyspnea x 3 days, CT
, alcoholism, liver ... /lung/kidney disease ... Skin #Infection #Cellulitis ... #Clinical #Photo ... #dermatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Sarcoidosis) • Liver ... autoimmune hepatitis, PBC ... Thalassemia, Sickle cell anemia ... Gap #ProteinGap #differential ... #diagnosis #hematology