23 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential ... disturbance (obstructed liver ... Highest • Bone • Liver ... #Differential # ... Diagnosis #Algorithm #hepatology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
HELLP - Grafts, Valves ... Drug-associated, PCH ... Defects, Drugs, Liver ... Defects: Sickle cell anemia ... #Diagnosis #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Bilirubin - +/- elevation ... Enzyme Elevation ... injury #hepatitis #differential ... diagnosis #algorithm #hepatology
Non-alcoholic fatty liver disease algorithm.
 
For those patients with NAFLD or liver disease of unknown aetiology,
fibrosis score with values ... markers such as ELF ... force impulse; ELF ... 4, fibrosis-4; HCC ... Referral #Management #Hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... to 10-20-fold elevation ... to 10-20-fold elevation ... #Disease #Pregnancy ... hepatitis #comparison #differential
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs R-value ... of cholestatic disease ... disease: > 2 ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... RBCs, muscle, liver ... - Prosthetic valves ... Idiosyncratic LDH Elevation ... Dehydrogenase #Elevated #differential
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
hallmark for the disease ... If the value is ... Mild-to-moderate elevation ... WBC count and differential ... Diagnosis #Workup #Hematology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
magnitude of enzyme elevation ... disease; AST, aspartate ... disease; T2DM, ... Abnormal #Algorithm #Hepatology ... #Differential #
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
from subclinical disease ... to acute liver ... hepatocellular pattern of liver ... reported (eg AIH-PBC ... (rare) - IgG Elevation