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hepatology diagnosis lfts injury transaminitis biliary causes chemistry cholangitis disease drug elevated fattyliver gastroenterology hepatitis idiosyncratic induced interpretation liverenzymes liverfunctiontests
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Calculate R-Value ... Idiosyncratic #differential ... gastroenterology #algorithm ... gastroenterology #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... • Iatrogenic: DILI ... hepatitis: < 1 • Cirrhosis ... #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Diagnosis Algorithm ... Congenital, Others, Cirrhosis ... #diagnosis #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Cirrhosis (PBC) ... /Liver failure ... or higher • Liver ... bile ducts Differential ... diagnosis #workup #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... Diagnosis Algorithm ... Bile Ducts • PSC ... Infiltrative • Cirrhosis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs R-value ... hepatitis: < 1 • Cirrhosis ... Unconjugated Bili ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Non-alcoholic fatty liver disease algorithm. For those patients with NAFLD or liver disease of unknown aetiology,
disease algorithm ... fibrosis score with values ... 4, fibrosis-4; HCC ... #Referral #Management ... #Hepatology
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