22 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... priapism • Lab values ... WBC >100k, + lab signs ... sudden death • Lab values ... #management #hematology
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Hyperviscosity Syndrome ... - Causes and Treatment ... - MH/CCF/CWRU EM ... #Causes #Differential ... #Management
Premature Ventricular Complexes (PVC's) - Summary Framework

Why PVCs?  Can be the first manifestation of cardiac
Inherited arrhythmia syndromes ... (e.g., long QT syndrome ... heart disease Causes ... A PAC also has a ... more intensive treatment
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
life-threatening Differential ... Generalized fatigue - ALS ... Serologic and EMG ... - Peek sign ... Gravis #diagnosis #management
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
carotid sinus syndrome ... syncope (ruling out differential ... further guide management ... orthostatic vital sign ... The treatment strategy
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... hyperthermia crisis (late sign ... #Hyperthermia #Differential ... #Causes #Anesthesiology ... Checklist #Diagnosis #Management
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup and Differential ... previously stable values ... hypertension and signs ... renal bruit or signs ... #Differential #
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... initiation • Differential ... fluid overload, PCC ... APML #diagnosis #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Medium and large also ... Behcet disease) Differential ... Treatment: • Oral ... #diagnosis #management ... #signs #symptoms
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
- Causes progressive ... EMG: LMN Signs in ... conditions listed in differential ... diagnosis column Treatment ... neurology #diagnosis #management