12 results
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Low intake • Metabolic ... Bartter syndrome, Gitelman ... #Differential # ... potassium #low #nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... cotransporter (NCC ... H+ secretion → Hypokalemia ... Metabolic alkalosis ... Pathophysiology #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
differentiating kidney ... Pressure: - Metabolic ... Bartter syndrome, Gitelman ... diagnosis #Algorithm #differential ... #potassium #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... hypomagnesemia • Metabolic ... Hypochloremic metabolic ... ratio 0.5%) Differential ... Syndrome #diagnosis #nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
patients with hypokalemia ... ↑ Aldosterone: Kidney ... Bartter syndrome, Gitelman ... urine #potassium #differential ... algorithm #diagnosis #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
alkalosis • Kidney ... Cl- outside the kidneys ... Bartter syndrome, Gitelman ... urine #Algorithm #nephrology ... #differential #
Gitelman Syndrome - Diagnosis and Workup
Blood Work:
 - Hypokalemia
 - Hypomagnesemia
 - Metabolic Alkalosis
 - Elevated
Gitelman Syndrome ... Blood Work: - Hypokalemia ... Hypomagnesemia - Metabolic ... autosomal dominant kidney ... Diagnosis #Workup #nephrology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Non-anion Gap Metabolic ... Chronic progressive kidney ... aniongap #NonGap #Metabolic ... #Acidosis #differential ... diagnosis #causes #nephrology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Hypochloremia - Differential ... - Bartter - Gitelman ... unloading • Kidney ... Hypochloremia #Differential ... Pathophysiology #Nephrology
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Causes of Metabolic ... Alkalosis: Differential ... furosemide-like lesion) • Gitelman ... #Alkalosis #Differential ... Diagnosis #Causes #nephrology