13 results
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Myasthenia Gravis ... life-threatening Differential ... Generalized fatigue - ALS ... Serologic and EMG ... failure - Can be
Multiple Cranial Neuropathies - High Yield Differential Diagnosis
 • Intrinsic brainstem process
 • Compressive brainstem process
Neurosarcoidosis • CNS ... important for facial weakness ... : • Myasthenia ... Gravis (much more ... #Diagnosis #causes
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Motor Nerves: ALS ... Eaton Syndrome, Myasthenia ... Gravis, Organophosphate ... aminoglycosides) • Muscles: Acid ... #Causes #differential
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
Myasthenia Gravis ... More likely to cause ... glucocorticoids - can cause ... #Gravis #diagnosis ... #management #neurology
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
Resp/Heme: CHF, valves ... Polyneuropathy, ALS ... NMJ disorder (Myasthenia ... Diagnosis #causes ... #neurology
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
And BMP Normal Values ... acidosis: - CNS ... Neuromuscular weakness ... (GBS, Myasthenia ... gravis) - Obstructive
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... Postsynaptic: Myasthenia ... Gravis - Lack ... #Differential # ... Diagnosis #neurology
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
PCR 50% sensitive ... lung nodules, may also ... see skin lesions ... Lesions #Brain #differential ... #diagnosis #causes
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... Demyelinating disease caused ... symptoms such as ... #Infections #differential ... InfectiousDiseases #Neurology
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
CNS Infections - ... /l is regarded as ... k_vaishnani and Ravi ... Singh @rav7ks #CNS ... #diagnosis #neurology