20 results
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
life-threatening Differential ... Generalized fatigue - ALS ... Serologic and EMG ... failure - Can be ... diagnosis #management #neurology
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
Resp/Heme: CHF, valves ... Polyneuropathy, ALS ... NMJ disorder (Myasthenia ... Diagnosis #causes ... #neurology
Multiple Cranial Neuropathies - High Yield Differential Diagnosis
 • Intrinsic brainstem process
 • Compressive brainstem process
Neurosarcoidosis • CNS ... Non-Neuropathy but also ... important for facial weakness ... : • Myasthenia ... #Diagnosis #causes
Myasthenia Gravis - Summary
 • an autoimmune disease of the postsynaptic neuromuscular junction associated with antibodies
serologic, and EMG ... More likely to cause ... or respiratory weakness ... glucocorticoids - can cause ... diagnosis #management #neurology
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Weakness • Spinal ... Motor Nerves: ALS ... Eaton Syndrome, Myasthenia ... #Causes #differential
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
PCR 50% sensitive ... lung nodules, may also ... see skin lesions ... Lesions #Brain #differential ... #diagnosis #causes
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... Postsynaptic: Myasthenia ... electromyographic (EMG ... #Differential # ... Diagnosis #neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... Demyelinating disease caused ... symptoms such as ... #Infections #differential ... InfectiousDiseases #Neurology
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
And BMP Normal Values ... acidosis: - CNS ... Neuromuscular weakness ... (GBS, Myasthenia ... Diagnosis #Summary #Nephrology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
nervous system (CNS ... is important, as ... Inflammatory causes ... #Syndromes #neurology ... #inflammatory #differential