10 results
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Diagnosis Hepatocellular ... Other: NAFLD, Autoimmune ... hepatitis, Acute ... #Injury #Differential
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Liver Injury ... injury - Viral ... Hepatitis - Autoimmune ... #Causes #Differential ... #Hepatology #Diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential ... Diagnosis Algorithm ... : Autoimmune hepatitis ... #injury #hepatitis
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
hepatitis Anti-CCP ... Dermatomyositis Anti-LKM (liver ... biliary cirrhosis (PBC ... Associations #diseases #diagnosis ... #table #rheumatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs R-value ... viral hepatitis ... viral hepatitis ... #chemistry #diagnosis ... #differential #
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Autoimmune Hepatitis ... subclinical disease to acute ... liver failure ... injury, though ... reported (eg AIH-PBC
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Diagnosis Framework ... RBCs, muscle, liver ... - Prosthetic valves ... : • Early acute ... hepatitisAcute
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... to bolus these values ... or renal injury ... Injury: • Reduced ... #typea #typeb #classification
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Sarcoidosis) • Liver ... Cirrhosis, ETOH, autoimmune ... hepatitis, PBC, ... PSC, Viral hepatitis ... #diagnosis #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... : • Acute cutaneous ... permanent alopecia Differential ... disease • Non-autoimmune ... Noninfectious hepatitis