21 results
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... HELLP - Grafts, Valves ... Drug-associated, PCH ... Defects: Sickle cell anemia ... #Diagnosis #hematology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Signs and Symptoms ... Diagnosis: • ... bile ducts Differential ... Diagnosis: • ... #workup #hepatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
neoplasms) • Screen also ... glucocorticoid treatment ... organ-specific signs ... Disorders #Algorithm #Differential ... #diagnosis #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
activity - A low value ... If the value is ... Haptoglobin - Low as ... WBC count and differential ... #Workup #Hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
• Symptoms of anemia ... anemia • Cold ... younger pts) Differential ... Disorders Such As ... #hematology #diagnosis
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... or sed rate): Value ... very remarkable w/differential ... systemic complaints- anemia ... Treatment of GCA
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
life-threatening Differential ... Generalized fatigue - ALS ... Serologic and EMG ... test - Cogan sign ... - Peek sign
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
of UMN and LMN signs ... of UMN and LMN signs ... EMG: LMN Signs in ... conditions listed in differential ... Treatment: - Multidisciplinary
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Hypertension - Workup ... and Differential ... Diagnosis Approach ... previously stable values ... renal bruit or signs
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... that a one-off value ... Better call hematology ... MPNs (MPL, CALR, also ... #workup #hematology