5 results
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... Dehydrogenase (LDH) - Differential ... enzymes - Acquired ... - Prosthetic valves ... Legionnaires disease • Pulmonary
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Defects: Sickle cell ... anemia, Thalassemias ... Haptoglobin ↓ - Lactate
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... e.g., uptake by cells ... to bolus these values ... output - Acute pulmonary ... 30mmHg) - Severe anemia
Community Acquired Pneumonia (CAP) - Diagnosis and Management

Pneumonia Signs/Symptoms:
 • Confusion/disorientation (LR + 1.9)
 • Cough
Community Acquired ... negative predictive value ... cultures/nasal PCR ... #Pulmonary #Community ... #Acquired
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
• No CRAB - no anemia ... lytic lesions • Lactate ... Bone marrow Treatment ... chemotherapy as required ... Oncology #Diagnosis #Workup