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hematology acidosis management algorithm causes cell classification elevation encephalopathy foamed hemolysis mental oncology plasmacytoma solitary status thromboticthrombocytopenicpurpura treatment ttp typea
Lactic Acidosis - Differential Diagnosis Framework Type A: Impaired O2 Delivery (DO2) • Decreased O2 Delivery: Hypotension
- Differential Diagnosis ... Shock, Severe Anemia ... Beta-Agonists, ↑ work ... #Acidosis #Differential ... #Diagnosis #criticalcare
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Acidosis - Differential ... www.ncbi.nlm.nih.gov/pmc ... to bolus these values ... 30mmHg) - Severe anemia ... #Elevation #Differential
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... HELLP - Grafts, Valves ... Drug-associated, PCH ... Defects: Sickle cell anemia ... Haptoglobin ↓ - Lactate
Acute Altered Mental Status - Rapid Response Management 1) Ask while en route: vitals, hyper/hypoactive, POC glucose,
Acute Altered Mental ... hyper/hypoactive, POC ... Workup 5) Treat ... status #Management #criticalcare ... encephalopathy #differential
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
activity - A low value ... If the value is ... elevation Serum lactate ... WBC count and differential ... #Workup #Hematology
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
hormones that work ... But we also have Lactic ... convert Pyruvate to Lactate ... #diagnosis #differential ... management #treatment #criticalcare
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Diagnosis? ... • No CRAB - no anemia ... lesions • Lactate ... myeloma Diagnostic ... #Workup #Hematology
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