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hematology causes criticalcare lactic management agglutinin algorithm anesthesia anesthesiology cardiacarrest checklist chronic classification cold disease elevation foamed gastroenterology hemolysis hemolytic
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
HELLP - Grafts, Valves ... Drug-associated, PCH ... Defects: Sickle cell ... anemia, Thalassemias ... Haptoglobin ↓ - Lactate
Lactic Acidosis - Differential Diagnosis Framework Type A: Impaired O2 Delivery (DO2) • Decreased O2 Delivery: Hypotension
- Differential Diagnosis ... Shock, Severe Anemia ... Beta-Agonists, ↑ work ... Difficult to diagnosis ... #Differential #
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
- Differential ... e.g., uptake by cells ... to bolus these values ... 30mmHg) - Severe anemia ... #Elevation #Differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
anemia • Cold ... Hyperbilirubinemia • Elevated lactate ... younger pts) Differential ... Disorders Such As ... sensitize red blood cells
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
activity - A low value ... If the value is ... elevation Serum lactate ... WBC count and differential ... #Workup #Hematology
Chronic Abdominal Pain Causes - Differential Diagnosis Framework Many patients with chronic abdominal pain have had prior
Pain Causes - Differential ... dysfunction • PSC ... malignancy • Lactase ... appendages • FMF ... Chronic #Causes #Differential
Cardiac Arrest - Guidelines for Crises in Anaesthesia The probable cause is one or more of: something
breathing system valves ... toxicity (→ 3-10) Acidosis ... CardiacArrest #Checklist #Differential ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
Ketosis (SK), acidosis ... hormones that work ... as well. ... convert Pyruvate to Lactate ... #diagnosis #differential
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Diagnosis? ... • No CRAB - no anemia ... lytic lesions • Lactate ... myeloma Diagnostic ... #Workup #Hematology
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