5 results
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
HELLP - Grafts, Valves ... Drug-associated, PCH ... Defects: Sickle cell ... anemia, Thalassemias ... Haptoglobin ↓ - Lactate
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Acidosis - Differential ... e.g., uptake by cells ... to bolus these values ... 30mmHg) - Severe anemia ... #Elevation #Differential
Community Acquired Pneumonia (CAP) - Diagnosis and Management

Pneumonia Signs/Symptoms:
 • Confusion/disorientation (LR + 1.9)
 • Cough
Community Acquired ... negative predictive value ... Inpatient Pneumonia: β-Lactam ... Inpatient Pneumonia: β-Lactam ... macrolide or β-lactam
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
Diagnosis? ... • No CRAB - no anemia ... lesions • Lactate ... required Prognosis ... #Workup #Hematology
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Complex (MAC): • Acquired ... Advanced HIV (CD4 cell ... enzymes, diarrhea, abdominal ... Bone Marrow - Anemia ... NTM #Infections #differential