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hematology acidosis agglutinin causes classification dehydrogenase elevated elevation hemolytic laboratory lactic thromboticthrombocytopenicpurpura ttp typea typeb
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Elevated Lactate ... ) - Differential ... , sickle cell disease ... - Prosthetic valves ... #LDH #Lactate
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Autoimmune: Warm AIHA, Cold ... Defects: Sickle cell ... anemia, Thalassemias
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Diagnosis: • hemolytic ... anemia • Cold ... Hyperbilirubinemia • Elevated lactate ... younger pts) Differential ... #hemolytic #anemia
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
hallmark for the disease ... elevation Serum lactate ... dehydrogenase (LDH ... WBC count and differential ... #Workup #Hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... e.g., uptake by cells ... to bolus these values ... presentations and disease ... 30mmHg) - Severe anemia
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