5 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
• Symptoms of anemia ... anemia • Cold ... Hyperbilirubinemia • Elevated lactate ... younger pts) Differential ... Disorders Such As
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... HELLP - Grafts, Valves ... Drug-associated, PCH ... Defects: Sickle cell anemia ... Haptoglobin ↓ - Lactate
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
hallmark for the disease ... If the value is ... elevation Serum lactate ... WBC count and differential ... #Workup #Hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... www.ncbi.nlm.nih.gov/pmc ... to bolus these values ... presentations and disease ... 30mmHg) - Severe anemia
Chronic Abdominal Pain Causes - Differential Diagnosis Framework

Many patients with chronic abdominal pain have had prior
Pain Causes - Differential ... dysfunction • PSC ... /AMI • PUD • ... malignancy • Lactase ... appendages • FMF