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hepatology hematology algorithm autoimmune causes hepatitis injury lactate liver rheumatology acidosis aih biliary celiac chemistry cholangitis cirrhosis classification clinicopathology dehydrogenase
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... hallmark for the disease ... Mild-to-moderate elevation ... WBC count and differential ... #Workup #Hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
normal or slightly elevated ... Normal early on but elevated ... Diagnosis: • ... bile ducts Differential ... #workup #hepatology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... HELLP - Grafts, Valves ... Drug-associated, PCH ... Hypophostphatemia Laboratory
Non-ACS Myocardial Injury - Elevated Troponin Differential Diagnosis and Workup Algorithm • Chronic Myocardial Injury: End
Myocardial Injury - Elevated ... Troponin Differential ... Diagnosis and Workup ... End Stage Renal Disease ... Occlusion • Stable
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... Diagnosis Framework ... - Prosthetic valves ... Idiosyncratic LDH Elevation ... diagnosis #Laboratory
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... Diagnosis Algorithm ... specificity to elevated ... Bilirubin - +/- elevation ... #diagnosis #algorithm
Commonly Used Diagnostic Tests for Celiac Disease Tissue transglutaminase (tTG) IgA antibodies - Most reliable noninvasive test
Commonly Used Diagnostic ... negative predictive value ... #Testing #Laboratory ... #Tests #Diagnosis ... #Workup #Table
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
from subclinical disease ... reported (eg AIH-PBC ... IgG typically elevated ... (rare) - IgG Elevation ... Necrosis) If mild laboratory
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... to bolus these values ... presentations and disease ... - assess other laboratory ... #Differential #
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs R-value ... specificity to elevated ... of cholestatic disease ... liver #chemistry #diagnosis ... #differential #
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