9 results
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... hallmark for the disease ... Mild-to-moderate elevation ... WBC count and differential ... #Workup #Hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... Fragmentation - MAHA: TTP ... HELLP - Grafts, Valves ... Drug-associated, PCH ... Hypophostphatemia Laboratory
Commonly Used Diagnostic Tests for Celiac Disease

Tissue transglutaminase (tTG) IgA antibodies
 - Most reliable noninvasive test
Commonly Used Diagnostic ... negative predictive value ... #Testing #Laboratory ... #Tests #Diagnosis ... #Workup #Table
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... Diagnosis Framework ... - Prosthetic valves ... Idiosyncratic LDH Elevation ... diagnosis #Laboratory
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... to bolus these values ... presentations and disease ... - assess other laboratory ... #Differential #
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Elevated Globulin ... Albumin > 4) Work-up ... of an Elevated ... #ProteinGap #differential ... #diagnosis #hematology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
with SPS have elevated ... antibody that works ... autoantibodies - TPO, TTG ... poisoning, Parkinson's disease ... Baclofen • Severe Disease
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... syndrome • Erythema elevatum ... Pseudohyponatremia • ↓anion gap ... Hematology #Monoclonal #Differential ... #Diagnosis #Oncology
Palpitations - Differential Diagnosis Framework

What?
• It is an unpleasant awareness or sensation that the heart is
Palpitations - Differential ... Diagnosis Framework ... ECG • Limited laboratory ... Have the patient tap ... palpitations: PVC