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causes algorithm secondary chronic elevatedmcv extravascular fatigue hemolytic macrocytic macrocytosis naildisorders neutropenia systemic thrombocytosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Membrane defects (e.g ... #diagnosis #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
malignancies • Anemia ... iron deficiency, hemolysis ... (e.g. autoimmune ... Myelodysplastic syndrome ... #hematology #secondary
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Diagnosis Algorithm ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Diagnosis Algorithm ... Neoplastic / Hematologic ... • Anemia • ... • Drug Abuse (e.g ... #Diagnosis #Algorithm
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... Iron deficiency anemia ... halt nail growth (e.g ... Systemic #Secondary #dermatology ... Diagnosis #Algorithm
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
Diagnosis Neonate ... hypertension and/or drug treatment ... , eg, cyclic neutropenia ... Megaloblastic anemia-rare ... #hematology
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