Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause - Maternal hypertension and/or drug treatment - Maternal antibody production - Constitutional disorders, eg, cyclic neutropenia, Kostmann syndrome, Chediak-Higashi syndrome Infant/child: - Infection-common - Autoimmune neutropenia - Neoplasms replacing the BM - Idiosyncratic drug reactions - Secondary autoimmune neutropenia in collagen vascular disorders - Immunodeficiency disorders - Myeloablative therapies - Constitutional neutropenia disorders-rare - Megaloblastic anemia-rare - Copper deficiency-rare Adult: - Idiosyncratic drug reactions-most common cause in ambulatory patients - Infections-common - Neoplasms replacing the BM-common - Myeloablative therapies-common - Secondary autoimmune neutropenia in collagen vascular disorders - Autoimmune disorders including white blood cell aplasia DOI: 10.1111/ijlh.13210 #Neutropenia #differential #diagnosis #causes #hematology
