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differential hematology management rash amiodarone anemia aplastic cryofibrinogenemia disorders dress eosinophilia erythroderma induced lung nikolsky oncology petechiae petechial physicalexam rheumatology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Testing Algorithm ... glucocorticoid treatment ... symptoms (eg, skin ... #Differential #diagnosis ... #hematology #eosinophilia
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Algorithm. ... Causes: 1) Exfoliative ... toxin 2) Eosinophils ... #Dermatology #Rash ... #Differential #Ddxof
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Definition: • Severe adverse drug reaction, characterized by
Edema in 70% of cases ... Criteria for Diagnosis ... Skin involvement ... disease: symptomatic treatment ... DRESS #Syndrome #dermatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... - Cholesterol embolism ... cryoglobulins • Skin ... #Algorithm #Causes ... #dermatology #physicalexam
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
starting amiodarone treatment ... rarely present with eosinophilic ... Exclude other causes ... embolism - ... macrophages Treatment
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
thrombophlebitis, pulmonary ... emboli, and ocular ... Cryofibrinogenemia Diagnosis ... cryoglobulins • Negative causes ... DIC • Septic emboli
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Headaches • Pale skin ... and petechiae Causes ... - Hepatitis, eosinophilic ... aplastic anemia Treatment ... #diagnosis #management
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