Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the epidermis 2) Inflammatory mediators result in dramatic increase of epidermal turnover rate, accelerated mitotic rate, increased number of germinative skin cells. Causes: 1) Exfoliative toxin 2) Eosinophils 3) Basophils/Histamine 4) Skin-homing T-cells #Diagnosis #Dermatology #Rash #Erythroderma #Nikolsky #Algorithm #Differential #Ddxof
