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diagnosis hematology neurology pulmonary signs adrenal amiodarone barre cardiology cardiomyopathy cushings dequervains differential encephalopathy gbs guillain hemeonc hemophagocytic hlh hypercortisolism
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... Dehydration • Symptoms ... changes, stroke symptoms ... unless worrisome EKG ... TLS #diagnosis #management
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... of diagnosis (e.g ... : (distinct symptoms ... Sarcoidosis #Diagnosis #Management ... #Signs #Symptoms
Adrenal Insufficiency - Diagnosis and Management Summary Primary Adrenal Insufficiency: Most Common Cause in the US: Autoimmune Adrenalitis Other
Diagnosis and Management ... ketoconazole, etomidate) Symptoms ... hypophysitis, Sheehan's syndrome ... Give 250 mcg of ... #Endocrinology
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features 1) Skin • Thin, easily bruisable skin with
exposed tothe sun (e.g ... , oral cavity) Caused ... gluconeogenesis enzymes (e.g ... Diagnosis #signs #symptoms ... #endocrinology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Neurological symptoms ... • EEG: With persistent ... the underlying cause ... with AEDs until cause ... #diagnosis #management
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal Syndromes ... recent DAN) • EMG ... or serologies + symptoms ... Goodpasture's cause ... differential #diagnosis #management
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... Incidence: 1 to 2 cases ... than one after symptom ... Electrodiagnostic studies (Ex EMG ... #diagnosis #management
Amiodarone Induced Lung Toxicity Summary Who? • 5% of patients • Dose ≥ 400 mg per day How? Possible
Acute toxicity (e.g ... respiratory distress syndrome ... Chronic toxicity (e.g ... Exclude other causes ... Pulmonary #diagnosis #management
Subacute Thyroiditis Also known as: de Quervain’s thyroiditis, granulomatous thyroiditis, or viral thyroiditis What? Postviral inflammatory process caused by
inflammatory process caused ... after onset Causes ... • Aspirin (e.g., ... #deQuervains #endocrinology ... thyroid #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
caused by uncontrolled ... ▪ Infections (e.g ... pro-inflammatory cytokines (e.g ... Immunosuppression (e.g ... anti-IFN-γ antibodies (e.g
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