98 results
Aplastic Anemia and Bone Marrow Failure Syndromes with Pancytopenia

Fanconi Anemia
Acquired Aplastic Anemia
Dyskeratosis Congenita & Telemore Biology
Marrow Failure Syndromes ... Telemore Biology Disorders ... Shwachman-Diamond Syndrome ... #Pancytopenia #Syndromes ... #diagnosis #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... lymphoproliferative disorders ... deficiencies (e.g ... differential #diagnosis #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... (e.g. lymphoma, ... (e.g. polycythemia ... vonWillebrand #Syndrome ... Management #treatment #hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
malignancies • Anemia ... Chronic inflammatory disorders ... (e.g. autoimmune ... Myelodysplastic syndrome ... Diagnosis #Causes #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Megakaryopoiesis • Aplastic Anemia ... Toxic Damage (e.g ... Displacement (e.g ... Non-lmmune: • HELLP Syndrome ... Foreign Surface (e.g
Causes of Excessive Daytime Sleepiness - Differential Diagnosis Algorithm
Insufficient Sleep
 • Poor Sleep Hygiene
 • Insomnia
Sleep Deprivation (Eg ... Restless Legs Syndrome ... (Eg. ... • Medications (Eg ... • Drug Abuse (Eg
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Increased Requirement (e.g ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... Algorithm #Causes #Hematology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Nail Disorders secondary ... Iron deficiency anemia ... halt nail growth (e.g ... • Nephrotic syndrome ... Systemic #Secondary #dermatology
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
Megaloblastic Anemia ... Microangiopathic hemolytic anemia ... (e.g. ... Autoimmune hemolytic anemia ... Smear #Analysis #hematology
Causes of Neutrophilia - Increased Neutrophils - Differential Diagnosis Algorithm
Infection
 • Bacterial
 • Abscess
 • Viral
Medications
Solid Tumour (e.g ... • Metabolic disorders ... Myeloproliferative Disorder ... Algorithm #Causes #Hematology