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diagnosis differential rheumatology antibodies autoantibodies autoimmune coagulation connectivetissuediseases crystals ctild deficiencies deficiency diseases hyperthermic ild lungdisease microscopy myopathy myositis pulmonary
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Associations ANA ... - Vasculitis, e.g ... - Vasculitis, e.g ... Autoantibodies #Associations ... #table #rheumatology
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
PSS: Sjogren syndrome ... #Differential #Comparison ... #Table #Pulmonary ... #Rheumatology # ... Associations
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Malabsorption (e.g ... warfarin, DOACs (e.g ... Autoimmune disorders (e.g ... #comparison #diagnosis ... #hematology #deficiency
Urine Microscopy Crystals Uric Acid crystals: - Formation promoted by acidic urine - Seen in tumor lysis
in tumor lysis syndrome ... specific systemic disease ... urease-producing organisms (e.g ... Microscopy #Crystals #comparison ... #table #urinalysis
Hyperthermic Toxidromes Five toxidromes may present with overlapping features: hyperthermia, rhabdomyolysis, altered mental status/seizures. • Sympathomimetic -
• Serotonin Syndrome ... dopamine blockers (e.g ... dopamine agonists (e.g ... pharmacogenetic disease ... #table #diagnosis
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Aldolase levels • EMG ... Antisynthetase syndrome ... (also seen in association ... paraneoplastic syndrome ... Myositis #Myopathy #rheumatology
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