9 results
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Acquired von Willebrand ... Syndrome - Diagnosis ... Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... Management #treatment #hematology
Raynaud's Syndrome - Washing off under hot water.
Raynaud phenomenon is an exaggerated vasoconstrictive response of the
Raynaud's Syndrome ... and arterioles (e.g ... #Raynauds #Syndrome ... water #fingers #hands ... #rheumatology
Raynaud's Syndrome - Washing off under hot water wath.

Raynaud phenomenon is an exaggerated vasoconstrictive response of
Raynaud's Syndrome ... and arterioles (e.g ... #Raynauds #Syndrome ... water #fingers #hands ... #rheumatology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
of Factor IX Acquired ... Malabsorption (e.g ... warfarin, DOACs (e.g ... Autoimmune disorders (e.g ... comparison #diagnosis #hematology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
La) - Sjogren's syndrome ... - Vasculitis, e.g ... - Vasculitis, e.g ... diseases #diagnosis #table ... #rheumatology #
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
the secondary or acquired ... underlying disease (eg ... • Infection (eg ... Diagnosis #Management #Hematology ... #Rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
not be subtle e.g ... E.g. 80 yo ESR cutoff ... variably: On one hand ... them, but urgent rheumatology ... w/in 24 hours) required
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
bleeding tendency is acquired ... Drug history, e.g ... connective tissue, e.g ... Marfan syndrome, ... pediatrics #diagnosis #hematology
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Aldolase levels • EMG ... RP-ILD), dermato-rheumatologic ... Antisynthetase syndrome ... • Mechanic's hands ... Myositis #Myopathy #rheumatology