11 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Subacute-Acute: • Common: fever ... #APML #diagnosis ... #management #hematology ... #oncology
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Hyperviscosity Syndrome ... hyperleukocytosis (AML ... - MH/CCF/CWRU EM ... #Differential #Diagnosis ... #Treatment #Management
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... - Workup and Management ... of the above Treatment ... #diagnosis #management ... #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... phenomenon CLL Diagnosis ... microglobulin Treatment ... • Richter’s Syndrome ... #workup #oncology
Septic Arthritis - Diagnosis and Management Summary
Clinical Exam: hot, swollen, pain with passive AND active ROM
and Management ... active ROM +/- fever ... viral arthritis Workup ... Treatment: admission ... MH/CCF/CWRU EM
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... Actively maintained fever ... • Serotonin syndrome ... Anesthesia #Checklist #Diagnosis ... #Management #Workup
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Presentation: • Fever ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... factor (GCSF) treatments ... Workup: • Complete ... #diagnosis #hematology ... #oncology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... leukoencephalopathy (PML ... Fever, chills, lack ... #Inflammatory #Syndrome ... #Management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... Hodgkin Lymphoma Workup ... Hodgkin Lymphoma Treatment ... classification #hematology #oncology ... #management