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arthritis differential pain approach signs symptoms testing calcium conditions cppd deposition extrarticular fungal igg4 infections infectiousdiseases laboratory mycoses phenotypes pseudogout
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... bacterial), acute rheumatic ... #Joint #Pain #MSK ... #rheumatology # ... approach #workup
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pulmonary ... • Interstitial lung ... , SLE • Pulmonary ... #differential #diagnosis ... #rheumatology
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Disease: • Pain ... in persons with rheumatoid ... #Pain #MSK #rheumatology ... #approach #workup ... #differential #diagnosis
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
(interstitial lung ... Musculoskeletal: joint ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... symptoms #testing #workup
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Scleromalacia perforans • Pulmonary ... : Parenchymal lung ... Musculoskeletal: Joint ... Signs #Symptoms #diagnosis ... #rheumatology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... antinuclear antibodies, rheumatoid ... #diagnosis #management ... #phenotypes #workup ... #treatment #rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... titer, ACE level, CXR ... #Disease #Rheumatoid ... #diagnosis #testing ... #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
: • 10%-15% Pulmonary ... phenomenon (16%) MSK ... MALT Lymphoma • Lung ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
("pseudo-rheumatoid ... culture used to diagnose ... ≥2 attacks • Long-term ... #Rheumatology # ... diagnosis #management
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
symptoms • Rheumatologic ... muscle aches, joint ... change in the lungs ... nails, bronchi, lungs ... #Management #Infections
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