9 results
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Pruritus - Generalized ... (dry skin) • Atopic ... renal failure/uremia ... #primary #secondary ... #causes
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Differential Diagnosis Algorithm ... Highest • Bone • Liver ... Intestine - Other causes ... - Fatigue - Pruritis ... #hepatology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm

Blood Glucose:
 • Diabetes Mellitus
Liver Function Tests/Enzymes:
Pruritus - No Primary ... renal failure/uremia ... #secondary #systemic ... #generalized #dermatology ... #causes
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Nail Disorders secondary ... Iron deficiency anemia ... discoloration) • Liver ... #Diagnosis #Algorithm ... #causes
Eczematous Skin Rash - Differential Diagnosis Algorithm
Eczematous - Pruritic/Scaly/Erythematous lesions. Usually poorly demarcated
 • Atopic Dermatitis
Eczematous - Pruritic ... demarcated • Atopic ... Secondary to venous ... #Eczematous #SkinRash ... #causes
Papulosquamous Skin Rash - Differential Diagnosis Algorithm
Erythrematous or violaceous papules & plaques with overlying scale
 •
Differential Diagnosis Algorithm ... Planus - Purple, pruritic ... central clearing • Secondary ... Papulosquamous #SkinRash ... #causes
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
synthesized in: liver ... pain • loss of secondary ... • Pernicious anemia ... Phosphatase: • Other causes ... Hyophosphatasia #hepatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... sweats, bleeding • Pruritis ... - infiltrates (anemia ... bone marrow and secondary ... #Leukemia #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
hyperinflammatory syndrome caused ... STX11, STXBP2 • Secondary ... - Cytopenias (anemia ... - Elevated liver ... Diagnosis #Management #Hematology