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Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
- Differential ... before beginning treatment ... output - Acute pulmonary ... edema - Mesenteric ... #Elevation #Differential
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... myalgias, HoTN, edema ... Imaging: CXR- pulmonary ... initiation • Differential ... Anaphylaxis, Acute Renal