23 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Coagulation Cascade ... twitter.com/AmyChung #AntiCoagulation ... #Medications #Pharmacology ... #Pathophysiology ... Mechanisms #DOAC #Hematology
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Anticoagulant #Anticoagulation ... #Dabigatran #Apixaban ... #Loading #DVT #Pharmacology ... #Hematology
Switching Between Anticoagulants and DOACs
VKA, Dabigatran, Rivaroxaban, Apixaban, Edoxaban, Betrixaban, DOAC, Parenteral anticoagulant

DOI: 10.1161/JAHA.120.017559

#Anticoagulants #DOACs #anticoagulation
, Rivaroxaban, Apixaban ... Anticoagulants #DOACs #anticoagulation ... #Switching #hematology ... #pharmacology
Diagram demonstrating TEG (thromboelastography) variables as they relate to the coagulation cascade.

Dr. Wells Brambl @DoctorWellsMD

#TEG #thromboelastography
the coagulation cascade ... #coagulation #cascade ... #anticoagulation ... #laboratory #hematology
Coagulation Cascade - Actions of Anticoagulants
 • Heparin: Unfractionated heparin, Enoxaparin, Daltaparin
 • Fondaparinux
 • Direct
Coagulation Cascade ... : Rivaroxaban, Apixaban ... #Coagulation #Cascade ... Anticoagulants #anticoagulation ... #pharmacology
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
(Praxbind) - Apixaban ... PCC (Kcentra) #anticoagulation ... #doac #noac #pharmacology ... #hematology #reversal
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
The coagulation cascade ... diagnosis #models #hematology ... #pathophysiology ... #anticoagulation ... thrombin #inhibitor #Apixaban
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet
Novel (or Direct) Oral Anti-Coagulants
 • Rivaroxaban
 • Apixaban
NOAC / DOAC Pharmacology ... Rivaroxaban • Apixaban ... #NOAC #DOAC #Pharmacology ... #Prescribing #hematology
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
Renal Dosing: Apixaban ... OralAnticoagulant #Anticoagulation ... #Hematology #Pharmacology ... #Apixaban #Rivaroxaban
Hemostasis Physiology

The blood's response to blood vessel injury can be viewed as four interrelated steps. 
Roman
#Hemostasis #Pathophysiology ... #Coagulation #Cascade ... #Hematology