18 results
Warfarin and DOAC Pharmacology
Warfarin - Dabigatran - Rivaroxaban - Apixaban - Edoxaban
Target - Prodrug - Bioavailability
Warfarin and DOAC ... Rivaroxaban - Apixaban - Edoxaban ... h) #Warfarin #DOAC ... #comparison #table ... rivaroxaban #apixaban #edoxaban
DOAC Cheat Sheet
 • Apixaban, Dabigatran, Edoxaban, Rivaroxaban
 • Renal Dosing
 • Common Drug interactions
 •
DOAC Cheat Sheet ... Apixaban, Dabigatran, Edoxaban ... Rivaroxaban • Renal Dosing ... DeLoughery @Bloodman #DOAC ... anticoagulation #CheatSheet #dosing
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
DOAC: Cheat Sheet ... Renal Dosing ... if CrCl < 50) Edoxaban ... @Bloodman #DOAC ... Rivaroxaban #Dabigatran #Edoxaban
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
stratification algorithm ... Currently, edoxaban ... being stronger for edoxaban ... for appropriate dosing ... #Cancer #Algorithm
Warfarin to DOAC and DOAC to Warfarin Transitions 

Here are a couple of charts to help
Warfarin to DOAC ... and DOAC to Warfarin ... for easier dosing ... Edoxaban is <2.5 ... #Pharmacology #Table
Comparison of oral anticoagulant agents (DOACS + Warfarin)

Reference: ENLS 2017 Pharmacotherapy. Neurocritical Care Journal.

#DOAC #Dosing #Oral
anticoagulant agents (DOACS ... #DOAC #Dosing #Oral ... Anticoagulation #Comparison #Table
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
anticoagulant dosing ... Clotmaster #VTE #DOAC ... #Bridging #Dosing ... #Rivaroxaban #Edoxaban
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
(DOAC interactions ... DOACs are substrates ... Edoxaban, rivaroxaban ... pathway whereas edoxaban ... #Interactions #Table
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Management of DOACs ... anticoagulants (DOACs ... clearance (calculated using ... per treatment table ... ) • Apixaban, Edoxaban
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
Treatment algorithm ... **Edoxaban is initiated ... bleeding risk during ... DOAC, direct oral ... #DOAC #VTE #Malignancy