17 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
anemia • Cold ... Positive Coombs testing ... Test: Donath-Landsteiner ... test #cold # ... #hematology #diagnosis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... Screening Tests ... Screening Tests ... #testing #Rheumatology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... inclusions - If infection ... #Differential #Diagnosis ... #testing
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
- Differential Diagnosis ... Internal (RBC) - Infections ... Defects: Sickle cell anemia ... Laboratory Tests ... #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... procedures - Infection ... smear, HIV/HCV testing ... K), H. pylori test ... changes), high MCV anemia
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Differential Diagnosis ... • Autoimmune diseases ... especially in the setting ... #differential #diagnosis ... neutrophil #WBC #CBC #hematology
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
for glomerular disease ... recommended for routine screening ... C3, C4 - Test for ... present) - These infections ... #workup #diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
SLE], AOSD) • Infection ... with leukopenia, anemia ... Liver function tests ... Activation #Syndrome #Diagnosis ... #Rheumatology
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... . 5) C3, C4 - Test ... recommended for routine screening ... present) - These infections ... #workup #diagnosis
CPPD vs Gout

== CPPD == 

Think About CPPD When:
 • Self-limited synovitis after surgery/trauma (> 65
shoulders, wrists, elbows ... • Underlying disease ... concomitant infection ... Synovial Fluid Testing ... Gout #Comparison #rheumatology