24 results
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Differential Diagnosis Algorithm ... Hemochromatosis • Wilson's Disease ... • Budd-Chiari Syndrome ... Primary Biliary Cirrhosis ... #Causes #Hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
>10 mmHg - clinically ... and hepatorenal syndrome ... • Budd Chiari syndrome ... /acute hepatitis ... Diagnosis #causes #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... • Cholestatic disease ... • Alcoholic hepatitis ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) Clinical ... those with CLD (± cirrhosis ... underlying liver disease ... (DILI) Viral Hepatitis ... #Hepatology #gastroenterology
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary Cirrhosis ... - Diagnosis Algorithm ... quadrant discomfort Signs ... Elevated ALP 2. ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
failure PBC Signs ... normal or slightly elevated ... Normal early on but elevated ... Diagnosis: • Viral hepatitis ... diagnosis #workup #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... vein: Budd-chiari syndrome ... specificity to elevated ... : < 1 • Cirrhosis ... #hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... Mild jaundice, Elevated ... necrosis HELLP Syndrome ... #Pregnancy #hepatology ... #obstetrics #hepatitis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
specificity to elevated ... of cholestatic disease ... : < 1 • Cirrhosis ... • Gilbert's syndrome ... #differential #Hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
from subclinical disease ... IgG typically elevated ... (eg Viral) Management ... AIH #Diagnosis #Management ... #Hepatology