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diagnosis rheumatology differential aflp autoimmune cvid disease erythematosus hellp hemeonc hemophagocytic hepatology hlh hypogammaglobulinemia icp immunodeficiency immunology liver lupus lymphohistiocytosis
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Mild jaundice, Elevated ... necrosis HELLP Syndrome ... (Hemolysis, Elevated ... #hepatology #obstetrics ... #hepatitis #comparison
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Gastrointestinal inflammatory ... Liver diseases and hepatitis ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... hypogammaglobulinemia #immunology #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
photosensitivity, inflammatory ... Malignancy (e.g. hematologic ... Noninfectious hepatitis ... sediment, and elevated ... Kidney disease common
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
mesenteric ischemia • Elevated ... Nodosa: • PAN most commonly ... Mono Multiplex, Elevated ... : Ocular inflammatory ... - interstitial keratitis
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Acquired) HLH: - Common ... Presentation • Common ... Overproduction of pro-inflammatory ... Elevated soluble ... #Hematology #HemeOnc
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
chondritis is the most common ... chondritis • Inflammatory ... loss, nausea Inflammatory ... SLE • RA - Most common ... #diagnosis #management
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Diagnosis Framework Inflammatory ... Myopathies: Commonly ... kinase levels are elevated ... PBC, autoimmune hepatitis ... Myositis #Myopathy #rheumatology
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