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diagnosis antibiotics febrile hematology infant lp peds risk stratification apml differentiation ebm leukostasis lysis tumor
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... organ damage • Treatment ... leukapheresis - TLS ... #TLS #diagnosis ... #management #hematology
“Step by Step” – the new kid on the block – aims to risk stratify this
investigations and treatments ... #Diagnosis #Management ... #Pediatrics #Peds ... Febrile #Infant #StepByStep ... #Algorithm #LP
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... if WBC > 5 or elevated ... Subacute-Acute: • Common: fever ... APML #diagnosis #management ... #hematology #oncology
The Febrile Infant Step-by-Step Algorithm This is an algorithm developed by European emergency physicians to identify low-risk
empiric antibiotic treatment ... Diagnosis #EBM #Management ... #Pediatrics #Peds ... Febrile #Infant #StepByStep ... Stratification #Fever
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