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diagnosis differential apml differentiation interpretation lfts liver monoclonal paraproteinemias rvalue transaminitis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... if WBC > 5 or elevated ... Differentiation #Syndrome ... APML #diagnosis #management ... #hematology #oncology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
specificity to elevated ... hepatitis: < 1 • Cirrhosis ... • Gilbert's syndrome ... Hemolysis #liver #chemistry ... #differential #Hepatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
capillary leak syndrome ... • Erythema elevatum ... Thrombosis in vascular beds-renal ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
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