355 results
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... edema, compartment syndrome ... Hemoconcentration: elevated ... of infections) ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... can mimic common infections ... >500 ng/mL • Elevated ... : • Infection ... Lymphohistiocytosis #diagnosis #management
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Diagnosis: • Infection ... CSF: Modestly elevated ... An elevated white ... epilepticus Treatment ... #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... if WBC > 5 or elevated ... Differential Diagnosis: Infection ... APML #diagnosis #management
Orthopedic Emergencies
Compartment Syndrome
 • An increase in compartment pressure to the point where tissue perfusion is
• Initial Management ... should not be elevated ... progressive inflammatory infection ... including DM • Treatment ... #treatment
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Puncture: - Elevated ... and cauda equina TREATMENT ... Guillain #Barre #Syndrome ... #diagnosis #management
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
vasculitis - Infectious ... fast bacterial infection ... Thrombocytopenia - Elevated ... Hypoalbuminemia Treatment ... TAFRO #diagnosis #management
IDSA Aspergillosis Treatment
 • Invasive pulmonary aspergillosis (IPA)
 • CNS aspergillosis
 • Cardiac Aspergillus infection
 •
Aspergillosis Treatment ... • Aspergillus infections ... of eye Infectious ... Aspergillosis #Treatment ... #management #pharmacology
Summary of Infections in which Steroids play a role in treatment
 • TB meningitis
 • TB
Summary of Infections ... play a role in treatment ... reconstitution inflammatory syndrome ... • Ramsay Hunt syndrome ... #management #treatment
Genital Lesions - Differential Diagnosis Algorithm
Elevated - Vesicles:
 • Herpes simplex
Elevated - Papules / Plaques -
Papules / Plaques - Infectious ... ) • Reiter's syndrome ... Plaques - Non-infectious ... Plaques - Non-infectious ... ) • Behcet's syndrome