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Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome:
 - Acute poststreptococcal 
glomerulonephritis 
 - Rapidly progressive
Glomerular Diseases ... glomerulonephritis - Berger disease ... Minimal change disease ... #Diseases #Nephritic ... #Diagnosis *
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup ... mimics, repeat testing ... • Evidence of glomerular ... for renal biopsy ... #urology #blood
Glomerular Diseases - Spectrum
 - Insidious vs Acute
 - Nephritic (hypertension, hematuria, renal failure) vs Nephrotic
Glomerular Diseases ... hypertension, hematuria, renal ... #Diseases #Spectrum ... #differential #diagnosis ... #nephrology
Nephrotic vs Nephritic syndromes - Spectrum of Glomerular Diseases 

#Nephritic #Nephrotic #Syndromes #Spectrum #Classification #Glomerular #Diseases
- Spectrum of Glomerular ... Diseases #Nephritic ... #Diseases #Nephrology ... #Diagnosis * ... GrepMed Recommended Text
Causes of Hematuria - Glomerular vs Non-glomerular

== Glomerular ==
- Glomerulonephritis 
- Thin basement membrane disease 

==
basement membrane disease ... Pyelonephritis - Renal ... Polycystic kidney disease ... #Algorithm #Diagnosis ... #Differential #Urology
Gitelman Syndrome - Diagnosis and Workup
Blood Work:
 - Hypokalemia
 - Hypomagnesemia
 - Metabolic Alkalosis
 - Elevated
and Workup Blood ... Elevated Renin Urine Testing ... renal Mg++ wasting ... dominant kidney disease ... #Workup #nephrology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Peripheral edema, Disease-specific ... vasculitis, Behcet disease ... Goodpasture's Disease ... dysmorphic RBCs) • Disease-specific ... testing: anti-ANCA
Causes of acute kidney injury (AKI). AKI is classified into pre-renal, renal, and post-renal causes. Renal
vascular supply; glomerular ... and interstitial disease ... GBM, Glomerular ... #Diagnosis #AKI ... Causes #Sites #Nephrology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
urine • 1ml blood ... basement membrane disease ... disease Renal ... #nephrology #renal ... #urine #blood
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
disease, but can ... of glomerular disease ... disease • Granular ... disease • “Muddy ... #nephrology #casts