41 results
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... age, however the disease ... : HLH signs and ... #management #treatment ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
) Pathophysiology ... accumulation of clinical ... Assessment • Clinical ... • Autoimmune diseases ... #management #treatment
Whipple Disease (Tropheryma whipplei) - Diagnosis and Management 

Caused by: Tropheryma whipplei

Symptoms and Signs:
1. Migratory poly/oligoarthralgia
Whipple Disease ... and Management ... Symptoms and Signs ... #diagnosis #algorithm ... #management #criteria
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
fever syndromes Clinical ... Fever is the main clinical ... Liver function tests ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
algorithm. ... symptoms/signs ... alcohol-related liver disease ... LFTs #Abnormal #Algorithm ... #Hepatology #Liver
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
common in Asia • HLA-B51 ... association • M > F Clinical ... Behcet syndrome (Clinical ... #management #signs ... #symptoms #rheumatology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... initial screening test ... causes of liver disease ... including liver and hematologic ... #diagnosis #management
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
and initial management ... HIT laboratory tests ... #Diagnosis #Management ... #Hematology #HIT ... Thrombocytopenia #Algorithm
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... back pain) • HLA-B27 ... (to support a diagnosis ... ANA and RF (if clinical ... laboratory #workup #diagnosis
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
Pott's Disease in ... extrapulmonary cases Clinical ... Signs/Symptoms: ... years - May have signs ... decreased reflexes Pathophysiology