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management differential tuberculosis latenttb bronchiectasis rheumatology syndrome active antigbm basement causes criteria erythematosus giomeruiar goodpastures hivaids idsa immune induration infections
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Tuberculosis Diagnosis ... Active TB: • ... : Active TB: • ... #Diagnosis #Management ... #Treatment #ActiveTB
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
Tuberculosis Diagnosis ... Active TB: • ... : Active TB: • ... #Diagnosis #Management ... #Treatment #ActiveTB
Tuberculosis Testing LATENT TB • LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
Testing LATENT TB ... • LTBI is diagnosed ... IGRA/QuantiFERON-TB ... intermediate risk of disease ... used to exclude pulmonary
Tuberculin Skin Test Interpretation - Threshold for treatment Induration cutoff >5mm: • Recent exposure to an individual
Tuberculin Skin Test ... Threshold for treatment ... individual with active ... TB • Abnormal ... #diagnosis #Interpretation
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Initial screening test ... Anti-dsDNA - 50% ... activity Anti-Ro ... Treatment: • ... #SLE #Summary #diagnosis
Bronchiectasis - Permanent dilation of an airway WHAT CAN YOU SEE ON CT? 1) Lack of tapering of
Dyskinesia, Alpha 1 Anti-trypsin ... Infection (Bacterial, TB ... Rheumatologic/Autoimmune diseae ... Bronchiectasis #pulmonary ... #diagnosis #differential
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis) Anti-basement ... life-threatening diseases ... Inflammatory eye disease ... ) Other tests: ... #management #treatment
IDSA Recommendations for Treating Mycobacterium Tuberculosis Infection and Disease in HIV-AIDS Treating LTBI (to prevent TB disease) Indications:
Infection and Disease ... (+) screening test ... , select anti-TB ... TB Disease: • ... and molecular diagnostic
Bronchiectasis - Summary What? • Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
Connective tissue diseases ... • Infection: TB ... , in advanced disease ... parenchyma Diagnosis ... mycobacteria Treatment
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
worsening of that disease ... , pulmonary infiltrates ... pericarditis, peritoneal disease ... lymphadenitis, pulmonary ... • Persistently active
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