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diagnosis rheumatology classification oncology signs syndrome vasculitis altered apml arteritis arthritis autoimmune biliary cholangitis cirrhosis criticalcare differentiation encephalopathy gca giantcell
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... Signs and Symptoms ... bile ducts Differential ... cholangitis #diagnosis #workup ... #hepatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
elbows/wrists and knees ... proximally to arms ... and Symptoms: ... pericarditis • Hepatic: PBC ... #workup
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
count cause hyperviscosity ... : - Neuro: AMS ... >100k, + lab signs ... TLS #diagnosis #management ... #hematology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
mononeuritis multiplex WORKUP ... w differential ... or serologies + symptoms ... Goodpasture's cause ... #diagnosis #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Imaging: CXR- pulmonary ... Diagnosis: >3 symptoms ... initiation • Differential ... APML #diagnosis #management ... #hematology #oncology
Acute Altered Mental Status - Rapid Response Management 1) Ask while en route: vitals, hyper/hypoactive, POC glucose,
hyper/hypoactive, POC ... is just a symptom ... Diagnosis and Workup ... the underlying cause ... encephalopathy #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... tract, and often causes ... Presentation - Systemic Symptoms ... purpura: strong sign ... Lab Tests: • CBC
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Presentation: Systemic Symptoms ... purpura: Strong sign ... • Progressive symptoms ... tract, and often causes
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Pain - Arthritis Differential ... , erythema and WBC ... noninflammatory Signs ... constitutional symptoms ... weeks) Can Be Caused
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
ingestion • B symptoms ... Hodgkin Lymphoma Workup ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
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